CellEDIT - Engineered Cell Lines

Let CellEDIT accelerate your research by creating your custom engineered cell line, allowing you to focus on your discoveries.

We’ll handle the CRISPR editing of your cell line, so you can run your experiment faster and finish your project sooner. 


Genome editing reagents are delivered into the cell through direct intranuclear injection without cargo-size limitations. By starting from injection of a defined number of reagents into single mammalian cells, we enable high editing precision and controllability. From knock-ins to knockouts, choose the CellEDIT service to outsource the generation of your engineered cells in 10 weeks.


Knockout 
Engineered Cell Lines

Save time in the lab by powering your research with CellEDIT. Confidently streamline your drug discovery workflow and investigate gene function with effective CRISPR knockouts. 


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Multiplex 
Editing of Cell Lines

At CellEDIT, we provide you with multiplexed cell lines in 10 weeks. The efficiency and gentleness of our vector-free editing through intra-nuclear delivery, makes it an ideal system to perform multiplex gene editing in one go. 


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Knockout Engineered Cell Lines

Access Knockout CRISPR Cell Lines without sacrificing time with CellEDIT's precision editing by direct intra-nuclear delivery of RNPs. In 10 weeks, we provide you with knockout monoclonal cell lines suited to your project needs.


CellEDIT Engineered Cell Lines - Cytosurge

Efficient on 
Hard-to-transfect cells

CellEDIT Engineered Cell Lines - Cytosurge

Vector-free 
direct intra-nuclear delivery

CellEDIT Engineered Cell Lines - Cytosurge

Minimized Off-Target

Immortalized Cell Lines


Learn how the CellEDIT workflow was used to generate 5 monoclonal Hprt knockouts in C2C12 cell line through direct intra-nuclear injection of only 51 cells.

Cancer Cell Lines

Discover how the CellEDIT workflow was used to produce 3 monoclonal HPRT1 knockouts in SK-MES-1 cell, a notoriously hard-to-transfect cell line.

Your Cells & Edits. Our Expertise.

Browse our custom cell lines: from hard-to-transfect to breast cancer cells, explore our CRISPR-edited cell lines through intra-nuclear delivery.

U2OS Cell Line

The U2OS cell line was derived in 1964 from a moderately differentiated tibial sarcoma from a 15-year-old female. The cell line displays epithelial morphology.

Customize your U2OS Cell Line

CHO Cell Line

The CHO cell line was derived from an ovarian biopsy of an adult female Chinese hamster in 1957, is widely used in industrial biotechnology and toxicology research. 
 

Configure your CHO Cell Line

HeLa Cell Line

HeLa cells represent the first immortal human cells to be grown in culture and the basis for countless significant scientific breakthroughs. 
 

Customize your HeLa Cell Line

MCF-7 Cell Line

The MCF-7 cell line was derived from a human breast adenocarcinoma and is widely used in biomedical research and industrial applications.
 

Configure your MCF-7 Cell Line

C2C12 Cell Line

C2C12 is a mouse myoblast cell line which quickly differentiates to form contractile myotubes and produce characteristic muscle proteins.

Customize your C2C12 Cell Line

HEK293 Cell Line

HEK293 is an epithelial cell line derived from the kidney of a human embryo. It is widely used in industrial biotechnology and toxicology research, with applications in efficacy and virucide testing.​
 

Configure your HEK293 Cell Line

MDA MB 231 Cell Line

The MDA MB 231 cell line was derived from a human breast adenocarcinoma.
 

Design your MDA MB 231 Cell Line

A549 Cell Line

A549 cells are lung carcinoma epithelial cells that are widely used in cancer research and drug discovery. 

Configure your A549 Cell Line

KPC Cell Line

The KPC cell line was derived from a genetically engineered mouse model of pancreatic ductal adenocarcinoma (PDAC).
 
Customize your KPC Cell Line

Multiplex Gene Editing of Cell Lines

Within 10 weeks, we perform for you, the multiplex editing of your targeted genes. CellEDIT's vector-free intra-nuclear delivery ensures efficient and gentle gene editing, making it the perfect solution for multiplex gene editing in a single step.

CellEDIT Engineered Cell Lines - Cytosurge

Efficient on 
Hard-to-transfect cells

CellEDIT Engineered Cell Lines - Cytosurge

Vector-free 
direct intra-nuclear delivery

CellEDIT Engineered Cell Lines - Cytosurge

Minimized Off-Target

We know the challenges you're facing with your CRISPR projects and the time you've spent in the lab, repeating over and over your transfection experiment, adding months to research deadlines. CellEDIT’s optimized transfection workflow along with our direct control over the CRISPR RNPs injected volume, minimizes off-target effect and maximizes editing efficiencies.

Explore how CellEDIT workflow boosted the editing efficiency in multiple KO CHO-K1 clones.

About the CellEDIT Service

CellEDIT provides specialized cell line engineering services using patented technology that surpasses conventional methods in delivering CRISPR complexes directly to the nucleus, ensuring high-quality cell line engineering for your research. Guided by our experts, each project is tailored to your needs - from gRNA design and cell culture methods to gentle yet efficient delivery and personalized quality controls - preserving cell integrity throughout the whole process.

We know the challenges you're facing with your CRISPR projects and the time you've spent in the lab, repeating over and over your transfection experiment, adding months to research deadlines. CellEDIT’s optimized transfection workflow along with our direct control over the CRISPR RNPs injected volume, minimizes off-target effect and maximizes editing efficiencies.